Advances In Biochemical Engineering Biotechnology by Bo Mattiasson, Lei Ye

By Bo Mattiasson, Lei Ye

Managed radical polymerization options for molecular imprinting, via Mark E. Byrne
From bulk polymers to nanoparticles, by means of Lei Ye
Post-imprinting and in-cavity functionalization, by way of Toshifumi Takeuchi
Characterization of MIPs (affinity, selectivity, website heterogeneity…), by means of Richard Ansell
Theoretical points and computing device modelling, by means of Ian Nicholls
MIPs in aqueous environments, via Bin Lu
MIPs for binding macromolecules, via Kenneth J. Shea
Solid part extraction, by means of Ecevit Yilmaz
Sensors, through Sergey A. Piletsky
MIPs for catalysis and synthesis, by means of Marina Resmini
Wastewater therapy, by way of Bo Mattiasson
MIPs as instruments for bioassays, biotransformation and drug supply, via Meiping Zhao

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49 Unsaturated Cyanohydrins . . . . . . . . . . . . 51 5 Conclusions and Outlook 6 References . . . . . . . . . . . . . . . . 53 . . . . . . . . . . . . g. biotransformations [1a–c, 2], will be very advantageous. In this respect, the hydroxynitrile lyases (Hnl) and their catalytic production of chiral cyanohydrins may have a significant role to play. The Hnls catalyse the asymmetric addition of hydrogen cyanide (HCN) to the carbonyl moiety of an aldehyde or ketone (Scheme 1) to yield a chiral cyanohydrin (1) (where R1 and R2 R1 = Alkyl or Aryl and R2 = H or Alkyl).

Kiljunen E, Kanerva LT (1996) Tetrahedron Asymmetry 7:1105 64. Kiljunen E, Kanerva LT (1997) Tetrahedron Asymmetry 8:1225 65. Kiljunen E, Kanerva LT (1997) Tetrahedron Asymmetry 8:1551 66. Bové C, Conn EE (1961) J Biol Chem 236:207 67. Woker R, Champluvier B, Kula M-R (1992) J Chromatogr 584:85 68. Niedermeyer U, Kula M-R (1990) Angew Chem Int Ed Engl 29:386, Angew Chem 102:423 69. Effenberger F, Hörsch B, Förster S, Ziegler T (1990) Tetrahedron Lett 31:1249 70. Chueshul S, Chulavatnatol M (1996) Arch Biochem Biophys 334:401 71.

Johnson · H. Griengl 42. (a) Zandbergen P, van der Linden J, Brussee J, van der Gen A (1991) Synth Commun 21:1387; (b) Zandbergen P, van der Linden J, Brussee J, van der Gen A (1995) Cyanohydrin formation. In: Roberts SM, Wiggins K, Casy G (eds) Preparative biotransformations: whole cell and isolated enzymes in organic synthesis. Wiley, New York, chap 4:51 43. Vernau J, Kula M-R (1990) Biotechnol Appl Biochem 12:397 44. Hasslacher M, Schall M, Hayn M, Bona R, Rumbold K, Lückl J, Griengl H, Kohlwein SD, Schwab H (1997) Protein Expression and Purif 11:61 45.

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